左力教授

现在北京大学人民医院肾内科工作，肾内科主任、教授、博士生导师。

教育经历：
1990年毕业于北京大学医学部医疗系；1996年获内科学博士学位，师从王海燕教授；2005年在美国肾病数据系统协调中心访问2年，师从Collins教授，学习透析登记数据的管理技术和生物统计学分析技术。

工作经历：
1990年始在北京大学第一医院内科工作，历任住院医、主治医、副主任医师、副教授和硕士生导师。2005年任内科主任医师；2007年任内科教授、博士生导师，2010年开始每年有2-3名博士生毕业，分布于我国北方多个城市。2013年调到北京大学人民医院肾内科工作至今。

社会任职：
现任中国医院协会血液净化中心管理分会主任委员、中国医疗设备协会血液净化设备技术委员会主任委员、北京生物医学工程协会血液净化分会副主任委员、北京市西城区血液净化质量控制和改进中心主任委员、《中国血液净化》杂志副主编、北京市血液净化质量控制和改进中心专家组成员、《中国全科医师杂志》编委。

基金：
已经完成的基金包括GFR种族差异的机制研究（北京市卫生局首发基金20万）；GFR简便评估方法的推广应用（北京市科委基金80万）；CKD早期诊断指标的开发、评估和验证（北京市科委基金350万）等。
正在执行的基金包括血液透析器膜改进（985课题基金300万）；尿毒症管理模式的研究（卫计委公益行业基金1300万）；定期使用生物电阻抗评估干体重改善血液透析患者预后的随机对照研究（横向课题150万）等。

兴趣领域：
导致慢性肾脏病进展的危险因素；开始肾脏替代治疗时机、血液透析管理、透析充分性研究。

正在进行的研究：
肝素导致骨质疏松的机制研究（研究者发起）；国际多中心随机对照试验ACTIVE D研究的中国区总负责人；国际多中心队列研究-透析预后与医疗模式研究（DOPPS）研究中国区总负责人。

近年发表的SCI论文：

已发表SCI论文总他引次数已接近1000次。2005年以来发表的部分SCI论文列表如下：

1.    Jian Y, Li X, Cheng X, Chen Y, Liu L, Tao Z, Zuo L. Comparison of bioimpedance and clinical methods for dry weight prediction in maintenance hemodialysis patients. Blood Purif. 2014;37(3):214-20. doi: 10.1159/000362109. Epub 2014 Jun5. PubMed PMID: 24902760.

2.    Bieber B, Qian J, Anand S, Yan Y, Chen N, Wang M, Wang M, Zuo L, Hou FF, Pisoni RL, Robinson BM, Ramirez SP. Two-times weekly hemodialysis in China: frequency, associated patient and treatment characteristics and Quality of Life in the China Dialysis Outcomes and Practice Patterns study. Nephrol Dial Transplant. 2014 Sep;29(9):1770-7. doi: 10.1093/ndt/gft472. Epub 2013 Dec 8.PubMed PMID: 24322579; PubMed Central PMCID: PMC4155454.

3.    Zhang K, Li Y, Cheng X, Liu L, Bai W, Guo W, Wu L, Zuo L. Cross-over study of influence of oral vitamin C supplementation on inflammatory status in maintenance hemodialysis patients. BMC Nephrol. 2013 Nov 14;14:252. doi:10.1186/1471-2369-14-252. PubMed PMID: 24228847; PubMed Central PMCID:PMC3840610.

4.    Meng Y, Zhang H, Li Y, Li Q, Zuo L. Effects of unfractionated heparin on renal osteodystrophy and vascular calcification in chronic kidney disease rats. Bone.2014 Jan;58:168-76. doi: 10.1016/j.bone.2013.10.010. Epub 2013 Oct 18. PubMed PMID: 24145307.

5.    Zuo L, Wang M; , for Beijing Blood Purification Quality Control and Improvement Center. Current status of maintenance hemodialysis in Beijing, China. Kidney Int Suppl (2011). 2013 May;3(2):167-169. PubMed PMID: 25018982; PubMed Central PMCID: PMC4089754.

6.    Kong X, Liu L, Zuo L, Yuan P, Li Z, Li W, Cai M, Chen X, Jiang A, Long G, Xu J, Lin H, Wang S, Huang W, Wang Y, Guo Y, Cao P, Wu H, Jia Q, Zhang L, Wang M, Wang H. Association between family members of dialysis patients and chronic kidney disease: a multicenter study in China. BMC Nephrol. 2013 Jan 18;14:19.doi: 10.1186/1471-2369-14-19. PubMed PMID: 23331610; PubMed Central PMCID:PMC3565899.

7.    Jia M, Cheng XY, Zuo L. In vitro phosphate-binding ability of calcium-based agents is augmented by co-administration of activated charcoal. Clin Nephrol.2013 Jun;79(6):471-6. doi: 10.5414/CN107713. PubMed PMID: 23253906.

8.    Kong X, Ma Y, Chen J, Luo Q, Yu X, Li Y, Xu J, Huang S, Wang L, Huang W, Wang M, Xu G, Zhang L, Zuo L, Wang H; Chinese eGFR Investigation Collaboration. Evaluation of the Chronic Kidney Disease Epidemiology Collaboration equation for estimating glomerular filtration rate in the Chinese population. Nephrol Dial Transplant. 2013 Mar;28(3):641-51. doi: 10.1093/ndt/gfs491. Epub 2012 Nov 29. PubMed PMID: 23197682.

9.    Liu L, Long G, Ren J, Li J, Xu J, Lei J, Li M, Qiu M, Yuan P, Sun W, Lin S,Liu W, Sun Y, Ma Y, Mao Y, Shen Y, Zuo L. A randomized controlled trial of long term effect of BCM guided fluid management in MHD patients (BOCOMO study):rationales and study design. BMC Nephrol. 2012 Sep 25;13:120. doi:10.1186/1471-2369-13-120. PubMed PMID: 23006960; PubMed Central PMCID:PMC3489516.

10.    Kong X, Zhang L, Zhang L, Chen N, Gu Y, Yu X, Liu W, Chen J, Peng L, Yuan W, Wu H, Chen W, Fan M, He L, Ding F, Chen X, Xiong Z, Zhang J, Jia Q, Shi W, Xing C, Tang X, Hou F, Shu G, Mei C, Wang L, Xu D, Ni Z, Zuo L, Wang M, Wang H. Mineral and bone disorder in Chinese dialysis patients: a multicenter study. BMC Nephrol. 2012 Sep 21;13:116. doi: 10.1186/1471-2369-13-116. PubMed PMID:22994525; PubMed Central PMCID: PMC3507668.

11.    Cheng X, Nayyar S, Wang M, Li X, Sun Y, Huang W, Zhang L, Wu H, Jia Q, Liu W,Sun X, Li J, Lun L, Zhou C, Cui T, Zhang A, Wang K, Wang S, Sun W, Zuo L. Mortality rates among prevalent hemodialysis patients in Beijing: a comparison with USRDS data. Nephrol Dial Transplant. 2013 Mar;28(3):724-32. doi:10.1093/ndt/gfs326. Epub 2012 Aug 20. PubMed PMID: 22907953.

12.    Zhang K, Dong J, Cheng X, Bai W, Guo W, Wu L, Zuo L. Association between vitamin C deficiency and dialysis modalities. Nephrology (Carlton). 2012Jul;17(5):452-7. doi: 10.1111/j.1440-1797.2012.01595.x. PubMed PMID: 22404236.

13.    Yang ZK, Dong J, Zuo L. [Faster decline of total fluid removal is an independent risk factor for increased mortality in patients on peritoneal dialysis]. Beijing Da Xue Xue Bao. 2011 Dec 18;43(6):844-8. Chinese. PubMed PMID:22178832.

14.    Quan L, Dong J, Li Y, Zuo L. The effectiveness of intensive nursing care onseasonal variation of blood pressure in patients on peritoneal dialysis. J Adv Nurs. 2012 Jun;68(6):1267-75. doi: 10.1111/j.1365-2648.2011.05833.x. Epub 2011Oct 27. PubMed PMID: 22032423.

15.    Dou Y, Cheng X, Liu L, Bai X, Wu L, Guo W, Zhao X, Wang F, Cao L, Zuo L. Development and validation of a new dry weight estimation method using single frequency bioimpedance in hemodialysis patients. Blood Purif. 2011;32(4):278-85. doi: 10.1159/000330337. Epub 2011 Aug 26. PubMed PMID: 21876350.

16.    Zhang K, Liu L, Cheng X, Dong J, Geng Q, Zuo L. Low levels of vitamin C in dialysis patients is associated with decreased prealbumin and increased C-reactive protein. BMC Nephrol. 2011 May 6;12:18. doi: 10.1186/1471-2369-12-18. PubMed PMID: 21548917; PubMed Central PMCID: PMC3112084.

17.    Dou Y, Liu L, Cheng X, Cao L, Zuo L. Comparison of bioimpedance methods for estimating total body water and intracellular water changes during hemodialysis. Nephrol Dial Transplant. 2011 Oct;26(10):3319-24. doi: 10.1093/ndt/gfq854. Epub2011 Mar 11. PubMed PMID: 21398364.

18.    Dong J, Li Y, Yang Z, Luo J, Zuo L. Time-dependent associations between total sodium removal and mortality in patients on peritoneal dialysis. Perit Dial Int.2011 Jul-Aug;31(4):412-21. doi: 10.3747/pdi.2010.00103. Epub 2011 Feb 28. PubMed PMID: 21357933.

19.    Wang F, Zhang L, Zuo L, Liu L, Wang H. Mortality and renal function decline among a community-based Chinese population with normal or mildly impaired renal function. Nephrol Dial Transplant. 2011 Sep;26(9):2847-52. doi:10.1093/ndt/gfq816. Epub 2011 Feb 1. PubMed PMID: 21285130.

20.    Zhuo M, Dong J, Zheng Y, Zuo L. Are ACEI/ARBs associated with the decreased peritoneal protein clearance in long-term PD patients? Nephrol Dial Transplant.2011 Aug;26(8):2684-90. doi: 10.1093/ndt/gfq764. Epub 2011 Jan 24. PubMed PMID:21262907.

21.    Su T, Zhang L, Li X, Zuo L, Zhang P, Wang H. Regular use of nephrotoxic medications is an independent risk factor for chronic kidney disease—results from a Chinese population study. Nephrol Dial Transplant. 2011 Jun;26(6):1916-23.doi: 10.1093/ndt/gfq679. Epub 2010 Nov 8. PubMed PMID: 21059833.

22.    Zuo L, Wang M; Chinese Association of Blood Purification Management of Chinese Hospital Association. Current burden and probable increasing incidence of ESRD in China. Clin Nephrol. 2010 Nov;74 Suppl 1:S20-2. PubMed PMID: 20979958.

23.    Xu R, Zhang LX, Zhang PH, Wang F, Zuo L, Wang HY. Gender differences in age-related decline in glomerular filtration rates in healthy people and chronic kidney disease patients. BMC Nephrol. 2010 Aug 23;11:20. doi:10.1186/1471-2369-11-20. PubMed PMID: 20731848; PubMed Central PMCID: PMC2936369.

24.    Xu R, Zuo L. Low birth weight and chronic kidney disease. Nephrology(Carlton). 2010 Jun;15 Suppl 2:18-22. doi: 10.1111/j.1440-1797.2010.01306.x.Review. PubMed PMID: 20586942.

25.    Bao Y, Zuo L. Effect of repeated freeze-thaw cycles on urinary albumin-to-creatinine ratio. Scand J Clin Lab Invest. 2009;69(8):886-8. doi:10.3109/00365510903323209. PubMed PMID: 19929272.

26.    Xu Y, Dong J, Zuo L. Is frequency of patient-physician clinic contact important in peritoneal dialysis patients? Perit Dial Int. 2009 Feb;29 Suppl2:S83-9. PubMed PMID: 19270238.

27.    Li Y, Dong J, Zuo L. Is subjective global assessment a good index of nutrition in peritoneal dialysis patients with gastrointestinal symptoms? PeritDial Int. 2009 Feb;29 Suppl 2:S78-82. PubMed PMID: 19270237.

28.    Xu R, Zhang L, Zhang P, Wang F, Zuo L, Wang H. Comparison of the prevalence of chronic kidney disease among different ethnicities: Beijing CKD survey and American NHANES. Nephrol Dial Transplant. 2009 Apr;24(4):1220-6. doi:10.1093/ndt/gfn609. Epub 2008 Nov 5. PubMed PMID: 18987261.

29.    Xu R, Zhang L, Zhang P, Wang F, Zuo L, Zhou Y, Shi Y, Li G, Jiao S, Liu Z, Xu G, Liang W, Wang H. Gender-specific reference value of urine albumin-creatinine ratio in healthy Chinese adults: results of the Beijing CKD survey. Clin ChimActa. 2008 Dec;398(1-2):125-9. doi: 10.1016/j.cca.2008.09.002. Epub 2008 Sep 10. PubMed PMID: 18809395.

30.    Zhang L, Zhang P, Wang F, Zuo L, Zhou Y, Shi Y, Li G, Jiao S, Liu Z, Liang W, Wang H. Prevalence and factors associated with CKD: a population study from Beijing. Am J Kidney Dis. 2008 Mar;51(3):373-84. doi: 10.1053/j.ajkd.2007.11.009.PubMed PMID: 18295053.

31.    Dong J, Li YJ, Lu XH, Gan HP, Zuo L, Wang HY. Correlations of lean body mass with nutritional indicators and mortality in patients on peritoneal dialysis. Kidney Int. 2008 Feb;73(3):334-40. Epub 2007 Nov 21. PubMed PMID: 18033246.

32.    Zhang L, Zuo L, Wang F, Wang M, Wang S, Liu L, Wang H. Metabolic syndrome and chronic kidney disease in a Chinese population aged 40 years and older. Mayo Clin Proc. 2007 Jul;82(7):822-7. PubMed PMID: 17605962.

33.    Li Q, Zhang CL, Fu ZL, Wang RF, Ma YC, Zuo L. Development of formulae for accurate measurement of the glomerular filtration rate by renal dynamic imaging. Nucl Med Commun. 2007 May;28(5):407-13. PubMed PMID: 17414891.

34.    Zhang L, Zuo L, Xu G, Wang F, Wang M, Wang S, Lv J, Liu L, Wang H. Community-based screening for chronic kidney disease among populations older than40 years in Beijing. Nephrol Dial Transplant. 2007 Apr;22(4):1093-9. Epub 2007Jan 8. PubMed PMID: 17210584.

35.    Zhang L, Zuo L, Wang F, Wang M, Wang S, Lv J, Liu L, Wang H. Cardiovascular disease in early stages of chronic kidney disease in a Chinese population. J AmSoc Nephrol. 2006 Sep;17(9):2617-21. Epub 2006 Aug 2. PubMed PMID: 16885404.

36.    Ma YC, Zuo L, Zhang CL, Wang M, Wang HY. [Comparison of single plasma sample methods and prediction of dual plasma sample method in measurement of99mTc-Diethylene Triamine Penta acetic Acid plasma clearance]. Beijing Da Xue Xue Bao. 2005 Dec 18;37(6):633-7. Chinese. PubMed PMID: 16378118.

37.    Zuo L, Wang M, Wei H, Feng LL. [Fluid distribution abnormalities and influence of hemodialysis on fluid distribution in patients on maintenance hemodialysis]. Beijing Da Xue Xue Bao. 2005 Oct 18;37(5):467-70. Chinese. PubMed PMID: 16224514.

38.    Zuo L, Ying-Chun, Wang M, Zhang CL, Wang RF, Wang HY. Prediction oftwo-sample (99m)Tc-diethylene triamine penta acetic acid plasma clearance from single-sample method. Ann Nucl Med. 2005 Jul;19(5):399-405. PubMed PMID:16164197.

39.    Zhang CL, Li Q, Zuo L, Cui Y, Wang YF, Guo FQ, Zhao GY, Zhang XC, Zhou YH, Wang RF. [Measurement of glomerular filtration rate with renal dynamic imaging: comparison with two-sample method]. Beijing Da Xue Xue Bao. 2004 Dec;36(6):612-5.Chinese. PubMed PMID: 15605093.

40.    Zuo L, Wang M, Wei H, Peng JX, Feng LL. [Assessment of total body water of patients on hemodialysis with urea kinetic model]. Beijing Da Xue Xue Bao. 2004Oct;36(5):533-5. Chinese. PubMed PMID: 15489938.